ITR2

Summary

Gene Symbol: ITR2
Description: myo-inositol transporter ITR2
Alias: HRB612, myo-inositol transporter ITR2
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Nikawa J, Tsukagoshi Y, Yamashita S. Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae. J Biol Chem. 1991;266:11184-91 pubmed
    ..and Yamashita, S. (1982) J. Bacteriol. 150, 441-446), we isolated two myo-inositol transporter genes, ITR1 and ITR2, from a yeast gene library...
  2. Miyashita M, Shugyo M, Nikawa J. Mutational analysis and localization of the inositol transporters of Saccharomyces cerevisiae. J Biosci Bioeng. 2003;96:291-7 pubmed
    Saccharomyces cerevisiae possesses two inositol transport proteins, Itr1p and Itr2p, encoded by the ITR1 and ITR2 genes, respectively. Itr1p and Itr2p are high and low affinity transporters, respectively...
  3. Yamagami K, Yamamoto T, Sakai S, Mioka T, Sano T, Igarashi Y, et al. Inositol depletion restores vesicle transport in yeast phospholipid flippase mutants. PLoS ONE. 2015;10:e0120108 pubmed publisher
    ..These results suggest that inositol depletion changes the lipid composition of the endosomal/TGN membranes, which results in vesicle formation from these membranes in the absence of flippases. ..