Gene Symbol: IME4
Description: mRNA (N6-adenosine)-methyltransferase
Alias: SPO8, mRNA (N6-adenosine)-methyltransferase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Shah J, Clancy M. IME4, a gene that mediates MAT and nutritional control of meiosis in Saccharomyces cerevisiae. Mol Cell Biol. 1992;12:1078-86 pubmed
    ..We describe a new gene, IME4, whose activity is essential for IME1 transcript accumulation and sporulation...
  2. Clancy M, Shambaugh M, Timpte C, Bokar J. Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene. Nucleic Acids Res. 2002;30:4509-18 pubmed
    ..The S.cerevisiae gene IME4, which is important for induction of sporulation, is very similar to the human gene MT-A70, which has been shown to ..
  3. Agarwala S, Blitzblau H, Hochwagen A, Fink G. RNA methylation by the MIS complex regulates a cell fate decision in yeast. PLoS Genet. 2012;8:e1002732 pubmed publisher
    ..We show that lineage restriction during this time was, in part, dependent on the mRNA methyltransferase activity of Ime4, which played separable roles in meiotic induction and suppression of the PH program...
  4. Yadav P, Rajasekharan R. The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells. J Biol Chem. 2017;292:13727-13744 pubmed publisher
    ..The role of yeast m6A methyltransferase, Ime4, in meiosis and sporulation in diploid strains is very well studied, but its role in haploid strains has remained ..