Genomes and Genes
Gene Symbol: HIR3
Alias: HPC1, Hir3p
Species: Saccharomyces cerevisiae S288c
- Nourani A, Robert F, Winston F. Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae. Mol Cell Biol. 2006;26:1496-509 pubmed..Taken together, our results suggest a direct link for Spt2 with transcription elongation, chromatin dynamics, and genome stability. ..
- Vishnoi N, Flaherty K, Hancock L, Ferreira M, Amin A, Prochasson P. Separation-of-function mutation in HPC2, a member of the HIR complex in S. cerevisiae, results in derepression of the histone genes but does not confer cryptic TATA phenotypes. Biochim Biophys Acta. 2011;1809:557-66 pubmed publisherThe HIR complex, which is comprised of the four proteins Hir1, Hir2, Hir3 and Hpc2, was first characterized as a repressor of three of the four histone gene loci in Saccharomyces cerevisiae...
- Georgakopoulos T, Koutroubas G, Vakonakis I, Tzermia M, Prokova V, Voutsina A, et al. Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways. Yeast. 2001;18:1155-71 pubmed..We found no unique phenotype attributed to the deletion of YGR223c. However, its function interferes with the function of the other two ORFs, as revealed by the effects of double- and triple-ORF deletions. ..
- Kuranda K, Grabinska K, Berges T, Karst F, Leberre V, Sokol S, et al. The YTA7 gene is involved in the regulation of the isoprenoid pathway in the yeast Saccharomyces cerevisiae. FEMS Yeast Res. 2009;9:381-90 pubmed publisher..Altogether, these results provide substantial evidence of Yta7p involvement in the regulation of isoprenoid biosynthesis. ..