Gene Symbol: HFD1
Description: hexadecenal dehydrogenase
Alias: hexadecenal dehydrogenase
Species: Saccharomyces cerevisiae S288c
Buijs N, Zhou Y, Siewers V, Nielsen J. Long-chain alkane production by the yeast Saccharomyces cerevisiae. Biotechnol Bioeng. 2015;112:1275-9 pubmed publisher
..We show that elimination of the hexadecenal dehydrogenase Hfd1 and expression of a redox system are essential for alkane biosynthesis in yeast...
Burri L, Vascotto K, Gentle I, Chan N, Beilharz T, Stapleton D, et al
. Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae. FEBS J. 2006;273:1507-15 pubmed
..The alpha-helical outer membrane proteins provide functions derived after the endosymbiotic event, and require the translocase in the outer mitochondrial membrane complex for insertion into the outer membrane. ..
Nakahara K, Ohkuni A, Kitamura T, Abe K, Naganuma T, Ohno Y, et al
. The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell. 2012;46:461-71 pubmed publisher
..We report here that yeast HFD1 and the Sjögren-Larsson syndrome (SLS)-causative mammalian gene ALDH3A2 are responsible for conversion of the ..
Currie E, Guo X, Christiano R, Chitraju C, Kory N, Harrison K, et al
. High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation. J Lipid Res. 2014;55:1465-77 pubmed publisher
..Our results provide a highly specific list of yeast LD proteins and reveal that the vast majority of these proteins are involved in lipid metabolism. ..
Payet L, Leroux M, Willison J, Kihara A, Pelosi L, Pierrel F. Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast. Cell Chem Biol. 2016;23:1241-1250 pubmed publisher
..of tyrosine to 4-hydroxyphenylpyruvate by Aro8 and Aro9, and the oxidation of 4-hydroxybenzaldehyde to 4-HB by Hfd1. Inactivation of the HFD1 gene in yeast resulted in Q deficiency, which was rescued by the human enzyme ALDH3A1...