Genomes and Genes
Gene Symbol: HEK2
Alias: KHD1, Hek2p
Species: Saccharomyces cerevisiae S288c
- Wolf J, Dowell R, Mahony S, Rabani M, Gifford D, Fink G. Feed-forward regulation of a cell fate determinant by an RNA-binding protein generates asymmetry in yeast. Genetics. 2010;185:513-22 pubmed publisher..We show that the RNA-binding protein Khd1 regulates asymmetric expression of FLO11 to determine daughter cell fate during filamentous growth...
- Tsvetanova N, Klass D, Salzman J, Brown P. Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae. PLoS ONE. 2010;5: pubmed publisher..Our results suggest that many more RBPs still remain to be identified and provide a set of candidates for further investigation. ..
- Kimura Y, Irie K, Irie K. Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b. Eukaryot Cell. 2013;12:864-74 pubmed publisher..In this study, we showed that PBP1 genetically interacts with CCR4 and KHD1, which encode a cytoplasmic deadenylase and an RNA-binding protein, respectively...
- Hirschmann W, Westendorf H, Mayer A, Cannarozzi G, Cramer P, Jansen R. Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Res. 2014;42:4043-55 pubmed publisher..Our data indicate that Scp160p might increase the efficiency of tRNA recharge, or prevent diffusion of discharged tRNAs, both of which were also proposed to be the likely basis for the translational fitness effect of tRNA pairing...