Gene Symbol: GRE2
Description: methylglyoxal reductase (NADPH-dependent) GRE2
Alias: methylglyoxal reductase (NADPH-dependent) GRE2
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Breicha K, Muller M, Hummel W, Niefind K. Crystallization and preliminary crystallographic analysis of Gre2p, an NADP(+)-dependent alcohol dehydrogenase from Saccharomyces cerevisiae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:838-41 pubmed publisher
    ..2 A. In spite of the monomeric nature of Gre2p in solution, packing and self-rotation calculations revealed the existence of two Gre2p protomers per asymmetric unit related by a twofold noncrystallographic axis. ..
  2. Teixeira M, Dujon B, Fabre E. Genome-wide nuclear morphology screen identifies novel genes involved in nuclear architecture and gene-silencing in Saccharomyces cerevisiae. J Mol Biol. 2002;321:551-61 pubmed
    ..Interestingly, these nuclear morphology alterations were associated with chromatin-silencing defects. These genes provide a molecular context to explore the functional link between nuclear architecture and gene silencing. ..
  3. Warringer J, Blomberg A. Involvement of yeast YOL151W/GRE2 in ergosterol metabolism. Yeast. 2006;23:389-98 pubmed
    The Saccharomyces cerevisiae gene YOL151W/GRE2 is widely used as a model gene in studies on yeast regulatory responses to osmotic and oxidative stress...
  4. Hauser M, Horn P, Tournu H, Hauser N, Hoheisel J, Brown A, et al. A transcriptome analysis of isoamyl alcohol-induced filamentation in yeast reveals a novel role for Gre2p as isovaleraldehyde reductase. FEMS Yeast Res. 2007;7:84-92 pubmed
    ..Two of these (YEL071w/DLD3 and YOL151w/GRE2) appear to play important roles in filamentation...
  5. Chen C, Porubleva L, Shearer G, Svrakic M, Holden L, Dover J, et al. Associating protein activities with their genes: rapid identification of a gene encoding a methylglyoxal reductase in the yeast Saccharomyces cerevisiae. Yeast. 2003;20:545-54 pubmed
    ..We show that methylglyoxal reductase (NADPH-dependent) is encoded by GRE2 (YOL151w)...
  6. Proft M, Struhl K. MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction. Cell. 2004;118:351-61 pubmed
  7. Guo P, Bao Z, Ma X, Xia Q, Li W. Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2. Biochim Biophys Acta. 2014;1844:1486-92 pubmed publisher
    Saccharomyces cerevisiae Gre2 (EC1.1.1...