Gene Symbol: FAU1
Description: 5-formyltetrahydrofolate cyclo-ligase
Alias: 5-formyltetrahydrofolate cyclo-ligase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Rébora K, Laloo B, Daignan Fornier B. Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule. Genetics. 2005;170:61-70 pubmed
    ..Together our data clearly establish that AICAR is not just a metabolic intermediate but also acts as a true regulatory molecule. ..
  2. Holmes W, Appling D. Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae. J Biol Chem. 2002;277:20205-13 pubmed
    ..We have thus named the yeast gene encoding methenyltetrahydrofolate synthetase FAU1 (folinic acid utilization)...
  3. Saint Marc C, Hürlimann H, Daignan Fornier B, Pinson B. Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae. Curr Genet. 2015;61:633-40 pubmed publisher
    ..Here, we revisited the effect of AICAR on methionine requirement due to AICAR accumulation in the presence of the fau1 mutation invalidating folinic acid remobilization...