Gene Symbol: ECM2
Description: Ecm2p
Alias: SLT11, Ecm2p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Xu D, Field D, Tang S, Moris A, Bobechko B, Friesen J. Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing. Mol Cell Biol. 1998;18:2055-66 pubmed
    ..b>SLT11 encodes a new splicing factor and SLT22 encodes a new RNA-dependent ATPase RNA helicase (D. Xu, S. Nouraini, D...
  2. Ben Yehuda S, Dix I, Russell C, McGarvey M, Beggs J, Kupiec M. Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics. 2000;156:1503-17 pubmed
    ..We discuss the role played by these proteins in splicing and cell cycle progression. ..
  3. Xu D, Friesen J. Splicing factor slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosome. Mol Cell Biol. 2001;21:1011-23 pubmed
    ..These results suggest that the function of Slt11p is regulated by Slu7p in the spliceosome. ..
  4. Yang H, Tong J, Lee C, Ha S, Eom S, Im Y. Structural mechanism of ergosterol regulation by fungal sterol transcription factor Upc2. Nat Commun. 2015;6:6129 pubmed publisher
    ..Our findings highlight that Upc2 represents a novel class of fungal zinc cluster transcription factors, which can serve as a target for the developments of antifungal therapeutics. ..