ECM1

Summary

Gene Symbol: ECM1
Description: Ecm1p
Alias: Ecm1p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Bassler J, Grandi P, Gadal O, Lessmann T, Petfalski E, Tollervey D, et al. Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell. 2001;8:517-29 pubmed
    ..Eight of these proteins were copurified with nuclear pore complexes, suggesting that this complex represents the transport intermediate for 60S subunit export. ..
  2. Yao Y, Demoinet E, Saveanu C, Lenormand P, Jacquier A, Fromont Racine M. Ecm1 is a new pre-ribosomal factor involved in pre-60S particle export. RNA. 2010;16:1007-17 pubmed publisher
    ..Here, we report the identification of a novel pre-60S factor, Ecm1, which partially acts like Arx1 and becomes essential when the NPC function is affected...
  3. Albanèse V, Reissmann S, Frydman J. A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis. J Cell Biol. 2010;189:69-81 pubmed publisher
    ..Our results demonstrate that, in addition to their known cytoplasmic roles in de novo protein folding, some ribosome-anchored CLIPS chaperones play a critical role in nuclear steps of ribosome biogenesis. ..
  4. Gao Q, Madian A, Liu X, Adamec J, Regnier F. Coupling protein complex analysis to peptide based proteomics. J Chromatogr A. 2010;1217:7661-8 pubmed publisher
  5. Ting Y, Lu T, Johnson A, Shie J, Chen B, Kumar S S, et al. Bcp1 Is the Nuclear Chaperone of Rpl23 in Saccharomyces cerevisiae. J Biol Chem. 2017;292:585-596 pubmed publisher
    ..Loss of Bcp1 causes instability of Rpl23 and deficiency of 60S subunits. In summary, Bcp1 is a novel 60S biogenesis factor via chaperoning Rpl23 in the nucleus. ..
  6. Martin D, Kim H, Mackin N, Maldonado Baez L, Evangelista C, BEAUDRY V, et al. New regulators of a high affinity Ca2+ influx system revealed through a genome-wide screen in yeast. J Biol Chem. 2011;286:10744-54 pubmed publisher
    ..Conservation of this quality control system in Candida glabrata suggests that many pathogenic species of fungi may utilize HACS and calcineurin to resist azoles and other compounds that target membrane biosynthesis. ..
  7. Lussier M, White A, Sheraton J, Di Paolo T, Treadwell J, Southard S, et al. Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics. 1997;147:435-50 pubmed
    ..Fifty of these genes were previously known, 17 encoded proteins whose function could be anticipated through sequence homology or previously recognized phenotypes and 15 genes had no previously known phenotype. ..
  8. Comino A, Mancek M, Komel R. Ecm11 is located in the cell nucleus throughout mitosis. Pflugers Arch. 2001;442:R179-81 pubmed
    ..According to our observation, we suppose that Ecm11 is a nuclear protein involved in the upholding chromatin structure. ..
  9. Occhipinti L, Chang Y, Altvater M, Menet A, Kemmler S, Panse V. Non-FG mediated transport of the large pre-ribosomal subunit through the nuclear pore complex by the mRNA export factor Gle2. Nucleic Acids Res. 2013;41:8266-79 pubmed publisher
    ..We propose that large complex cargos rely on non-FG as well as FG-interactions for their efficient translocation through the nuclear pore complex channel. ..