DLD3

Summary

Gene Symbol: DLD3
Description: D-lactate dehydrogenase
Alias: D-lactate dehydrogenase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Chelstowska A, Liu Z, Jia Y, Amberg D, Butow R. Signalling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity in yeast. Yeast. 1999;15:1377-91 pubmed
    ..Our data thus provide gene assignments for two previously unrecognized D-lactate dehydrogenase activities in yeast. ..
  2. Hauser M, Horn P, Tournu H, Hauser N, Hoheisel J, Brown A, et al. A transcriptome analysis of isoamyl alcohol-induced filamentation in yeast reveals a novel role for Gre2p as isovaleraldehyde reductase. FEMS Yeast Res. 2007;7:84-92 pubmed
    ..Two of these (YEL071w/DLD3 and YOL151w/GRE2) appear to play important roles in filamentation...
  3. Mokranjac D, Sichting M, Popov Celeketic D, Mapa K, Gevorkyan Airapetov L, Zohary K, et al. Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell. 2009;20:1400-7 pubmed publisher
    ..This function of Tim50 depends on its association with TIM23. We conclude that the efficient transfer of precursors between TOM and TIM23 complexes requires the concerted action of Tim50 with Tim23. ..
  4. Lee J, Ishida Y, Kuge S, Naganuma A, Hwang G. Identification of substrates of F-box protein involved in methylmercury toxicity in yeast cells. FEBS Lett. 2015;589:2720-5 pubmed publisher
    ..In this study, we found that Dld3 and Grs1 bound to Hrt3 and that Eno2 bound to Ucc1 using a yeast two-hybrid screening...
  5. Becker Kettern J, Paczia N, Conrotte J, Kay D, Guignard C, Jung P, et al. Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase. J Biol Chem. 2016;291:6036-58 pubmed publisher
    ..human D-2HG dehydrogenase: Dld2, which, as its human homolog, is a mitochondrial protein, and the cytosolic protein Dld3. Intriguingly, we found that a dld3Δ knock-out strain accumulates millimolar levels of D-2HG, whereas a dld2Î..