Genomes and Genes
Gene Symbol: CWH41
Alias: DER7, GLS1, Cwh41p
Species: Saccharomyces cerevisiae S288c
- Runge K, Robbins P. A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway. Formation of a novel asparagine-linked oligosaccharide containing two glucose residues. J Biol Chem. 1986;261:15582-90 pubmed..The yeast mutation gls1-1 lacks glucosidase I activity (Esmon, B., Esmon, P.C., and Schekman, R. (1984) J. Biol. Chem...
- Simons J, Ebersold M, Helenius A. Cell wall 1,6-beta-glucan synthesis in Saccharomyces cerevisiae depends on ER glucosidases I and II, and the molecular chaperone BiP/Kar2p. EMBO J. 1998;17:396-405 pubmed..In S.cerevisiae, glucosidase II is encoded by the GLS2 gene, and glucosidase I, as suggested here, by the CWH41 gene...
- Abeijon C, Chen L. The role of glucosidase I (Cwh41p) in the biosynthesis of cell wall beta-1,6-glucan is indirect. Mol Biol Cell. 1998;9:2729-38 pubmed..To distinguish between a direct or indirect role of Cwh41p in the biosynthesis of beta-1,6-glucan, we constructed a double mutant, alg5Delta (lacking dolichol-P-glucose ..
- Faridmoayer A, Scaman C. Truncations and functional carboxylic acid residues of yeast processing alpha-glucosidase I. Glycoconj J. 2007;24:429-37 pubmedYeast alpha-glucosidase I (Cwh41p) encoded by CWH41 is an endoplasmic reticulum (ER) membrane-bound glycoprotein (833 residues), which plays an important role in the early steps of the N-glycosylation pathway...
- Shibuya A, Margulis N, Christiano R, Walther T, Barlowe C. The Erv41-Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins. J Cell Biol. 2015;208:197-209 pubmed publisher..In cells lacking Erv41-Erv46 function, the ER enzyme glucosidase I (Gls1) was mislocalized and degraded in the vacuole...