Gene Symbol: CSM4
Description: Csm4p
Alias: Csm4p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Rabitsch K, Toth A, Galova M, Schleiffer A, Schaffner G, Aigner E, et al. A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol. 2001;11:1001-9 pubmed
    ..Reverse genetics using gene expression data is an effective method for identifying new genes involved in specific cellular processes. ..
  2. Conrad M, Lee C, Chao G, Shinohara M, Kosaka H, Shinohara A, et al. Rapid telomere movement in meiotic prophase is promoted by NDJ1, MPS3, and CSM4 and is modulated by recombination. Cell. 2008;133:1175-87 pubmed publisher
    ..Bouquet formation and RPMs depend on NDJ1, MPS3, and a new member of this pathway, CSM4, which encodes a meiosis-specific nuclear envelope protein required specifically for telomere mobility...
  3. Beilharz T, Egan B, Silver P, Hofmann K, Lithgow T. Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. J Biol Chem. 2003;278:8219-23 pubmed
  4. Kosaka H, Shinohara M, Shinohara A. Csm4-dependent telomere movement on nuclear envelope promotes meiotic recombination. PLoS Genet. 2008;4:e1000196 pubmed publisher
    ..Here, we show that a meiosis-specific protein, Csm4, which forms a complex with Ndj1, facilitates bouquet formation...
  5. Sonntag Brown M, Zanders S, Alani E. Sustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast. Genetics. 2011;188:21-32 pubmed publisher
    ..We found that csm4? strains, which are defective for telomere-led chromosome movements, show defects in homolog pairing as measured in ..
  6. Wu H, Ho H, Burgess S. Mek1 kinase governs outcomes of meiotic recombination and the checkpoint response. Curr Biol. 2010;20:1707-16 pubmed publisher
    ..We discuss how regulation of pachytene exit by Mek1 or similar kinases could influence checkpoint stringency, which may differ among species and between sexes. ..
  7. Chu D, Gromova T, Newman T, Burgess S. The Nucleoporin Nup2 Contains a Meiotic-Autonomous Region that Promotes the Dynamic Chromosome Events of Meiosis. Genetics. 2017;206:1319-1337 pubmed publisher
    ..These data suggest Nup2 and Ndj1 support partially overlapping functions that promote two different levels of meiotic chromosome organization necessary to withstand a dynamic stage of the eukaryotic life cycle. ..
  8. Wanat J, Kim K, Koszul R, Zanders S, Weiner B, Kleckner N, et al. Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis. PLoS Genet. 2008;4:e1000188 pubmed publisher
    ..quot; In this study, we identify Csm4 as a new molecular participant in these processes and show that, unlike the two previously identified components, ..