Gene Symbol: COX9
Description: cytochrome c oxidase subunit VIIa
Alias: cytochrome c oxidase subunit VIIa
Species: Saccharomyces cerevisiae S288c
Geier B, Schagger H, Ortwein C, Link T, Hagen W, Brandt U, et al
. Kinetic properties and ligand binding of the eleven-subunit cytochrome-c oxidase from Saccharomyces cerevisiae isolated with a novel large-scale purification method. Eur J Biochem. 1995;227:296-302 pubmed
..This high content of fast enzyme was also reflected in the characteristics of optical and EPR spectra for cytochrome-c oxidase purified with our method. ..
Strogolova V, Furness A, Robb McGrath M, Garlich J, Stuart R. Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex. Mol Cell Biol. 2012;32:1363-73 pubmed publisher
..Based on our findings, we propose a model where the Hig1 proteins regulate the COX enzyme activity through Cox3 and associated Cox12 protein, in a manner that may be influenced by the neighboring AAC proteins. ..
Zhao H, Wang Q, Liu C, Shang Y, Wen F, Wang F, et al
. A Role for the Respiratory Chain in Regulating Meiosis Initiation in Saccharomyces cerevisiae. Genetics. 2018;208:1181-1194 pubmed publisher
..In summary, our studies unveiled the close relationship between mitochondria and sporulation, and uncover a novel meiosis initiation pathway that is regulated by the respiratory chain. ..
Taanman J, Capaldi R. Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J Biol Chem. 1992;267:22481-5 pubmed
..The enzyme isolated in lauryl maltoside contains these same nine different polypeptides and three others, including homologues of subunits VIa and VIb of the mammalian enzyme. ..
Quarterman J, Skerker J, Feng X, Liu I, Zhao H, Arkin A, et al
. Rapid and efficient galactose fermentation by engineered Saccharomyces cerevisiae. J Biotechnol. 2016;229:13-21 pubmed publisher
..In order to force S. cerevisiae to use galactose without respiration, a subunit (COX9) of a respiratory enzyme was deleted, but the resulting deletion mutant (?cox9) was impaired in terms of galactose ..