Gene Symbol: COS8
Species: Saccharomyces cerevisiae S288c
MacDonald C, Payne J, Aboian M, Smith W, Katzmann D, Piper R. A family of tetraspans organizes cargo for sorting into multivesicular bodies. Dev Cell. 2015;33:328-42 pubmed publisher
..Expression of these proteins increases during nutrient stress through an NAD(+)/Sir2-dependent mechanism that in turn accelerates the downregulation of a broad range of cell-surface proteins. ..
Gulati S, Balderes D, Kim C, Guo Z, Wilcox L, Area Gomez E, et al
. ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification. FASEB J. 2015;29:4682-94 pubmed publisher
Bailly Bechet M, Borgs C, Braunstein A, Chayes J, Dagkessamanskaia A, Francois J, et al
. Finding undetected protein associations in cell signaling by belief propagation. Proc Natl Acad Sci U S A. 2011;108:882-7 pubmed publisher
..We identify the role of the COS8 protein, a member of a gene family of previously unknown function, and validate the results by genetic experiments...
Spode I, Maiwald D, Hollenberg C, Suckow M. ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes. J Mol Biol. 2002;319:407-20 pubmed
..of the SACE of the left arm of chromosome VIII in vivo and found its ATF/CREB site to act as UAS/URS of the COS8 promoter, effected by the yeast bZip proteins Sko1p, Aca1p, and Aca2p...