Gene Symbol: BDH1
Description: (R,R)-butanediol dehydrogenase
Alias: (R,R)-butanediol dehydrogenase
Species: Saccharomyces cerevisiae S288c
Gonzalez E, Fernández M, Marco D, Calam E, Sumoy L, Parés X, et al
. Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol. Appl Environ Microbiol. 2010;76:670-9 pubmed publisher
..Deletion of BDH1 resulted in an accumulation of acetoin and a diminution of 2,3-butanediol in two S...
Gonzalez E, Fernandez M, Larroy C, Sola L, Pericàs M, Pares X, et al
. Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J Biol Chem. 2000;275:35876-85 pubmed
..The corresponding enzyme is the first eukaryotic (2R, 3R)-2,3-butanediol dehydrogenase characterized of the medium-chain dehydrogenase/reductase family. ..
Cadiere A, Galeote V, Dequin S. The Saccharomyces cerevisiae zinc factor protein Stb5p is required as a basal regulator of the pentose phosphate pathway. FEMS Yeast Res. 2010;10:819-27 pubmed publisher
..Our data also demonstrate the potential use of a system based on overproduction of this transcription factor to increase flux through the PP pathway. ..
Calam E, GonzÃ¡lez Roca E, FernÃ¡ndez M, Dequin S, ParÃ©s X, Virgili A, et al
. Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase. Appl Environ Microbiol. 2016;82:1706-1721 pubmed publisher
..We have also developed a new variant of the delitto perfetto methodology to place BDH1 under the control of the GAL1 promoter, resulting in a yeast strain that overexpresses butanediol dehydrogenase and ..