Gene Symbol: BAP2
Description: branched-chain amino acid permease BAP2
Alias: branched-chain amino acid permease BAP2
Species: Saccharomyces cerevisiae S288c
Usami Y, Uemura S, Mochizuki T, Morita A, Shishido F, Inokuchi J, et al
. Functional mapping and implications of substrate specificity of the yeast high-affinity leucine permease Bap2. Biochim Biophys Acta. 2014;1838:1719-29 pubmed publisher
..leucine uptake is mediated by multiple amino acid permeases, including the high-affinity leucine permease Bap2. Although BAP2 transcription has been extensively analyzed, the mechanisms by which a substrate is recognized and ..
Regenberg B, Düring Olsen L, Kielland Brandt M, Holmberg S. Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet. 1999;36:317-28 pubmed
..On a non-repressive nitrogen source, AGP1 is induced, while GLN1, BAP2 and BAP3 are not...
Liu M, Brusilow W, Needleman R. Activity of the yeast Tat2p tryptophan permease is sensitive to the anti-tumor agent 4-phenylbutyrate. Curr Genet. 2004;46:256-68 pubmed
Wolf W, Meese K, Seedorf M. Ist2 in the yeast cortical endoplasmic reticulum promotes trafficking of the amino acid transporter Bap2 to the plasma membrane. PLoS ONE. 2014;9:e85418 pubmed publisher
..timer protein tag showed that Ist2 was necessary for efficient trafficking of newly synthesized leucine transporter Bap2 from the ER to the plasma membrane...
Wright M, Ramos J, Gomez M, Moulder K, Scherrer M, Munson G, et al
. Potassium transport by amino acid permeases in Saccharomyces cerevisiae. J Biol Chem. 1997;272:13647-52 pubmed
..Molecular analysis revealed the suppressor to be an allele of BAP2 that encodes a permease for branched chain amino acids...
Merhi A, Gérard N, Lauwers E, Prevost M, Andre B. Systematic mutational analysis of the intracellular regions of yeast Gap1 permease. PLoS ONE. 2011;6:e18457 pubmed publisher
..Interestingly, this direct vacuolar sorting seems to be independent of Gap1 ubiquitylation. This study illustrates the importance of multiple intracellular regions of Gap1 in its secretion, transport activity, and down-regulation. ..
Popov Celeketic D, Bianchi F, Ruiz S, Meutiawati F, Poolman B. A Plasma Membrane Association Module in Yeast Amino Acid Transporters. J Biol Chem. 2016;291:16024-37 pubmed publisher
..Using in silico analyses and mutational studies we found that the C-terminal sequences of Gap1, Bap2, Hip1, Tat1, Tat2, Mmp1, Sam3, Agp1, and Gnp1 are about 50 residues long, associate with the PM, and have features ..