Gene Symbol: ATP11
Species: Saccharomyces cerevisiae S288c
Ackerman S, Tzagoloff A. Identification of two nuclear genes (ATP11, ATP12) required for assembly of the yeast F1-ATPase. Proc Natl Acad Sci U S A. 1990;87:4986-90 pubmed
..The two wild-type nuclear genes defined by the mutants have been designated ATP11 and ATP12...
Wang Z, Ackerman S. The assembly factor Atp11p binds to the beta-subunit of the mitochondrial F(1)-ATPase. J Biol Chem. 2000;275:5767-72 pubmed
b>Atp11p is a protein of Saccharomyces cerevisiae required for the assembly of the F(1) component of the mitochondrial F(1)F(0)-ATP synthase. This study presents evidence that Atp11p binds selectively to the beta-subunit of F(1)...
Schwimmer C, Lefebvre Legendre L, Rak M, Devin A, Slonimski P, di Rago J, et al
. Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. J Biol Chem. 2005;280:30751-9 pubmed
..This unexpected result might be of interest for the development of therapeutic solutions in pathologies associated with defects in the oxidative phosphorylation system. ..
Linderholm A, Findleton C, Kumar G, Hong Y, Bisson L. Identification of genes affecting hydrogen sulfide formation in Saccharomyces cerevisiae. Appl Environ Microbiol. 2008;74:1418-27 pubmed publisher
..In most cases, creation of multiple deletions of the 16 mutations in the same strain did not lead to a further increase in H(2)S production, instead often resulting in decreased levels. ..
Ackerman S, Martin J, Tzagoloff A. Characterization of ATP11 and detection of the encoded protein in mitochondria of Saccharomyces cerevisiae. J Biol Chem. 1992;267:7386-94 pubmed
In Saccharomyces cerevisiae, expression of functional F1-ATPase requires two proteins encoded by the ATP11 and ATP12 genes...
Hinton A, Zuiderweg E, Ackerman S. A purified subfragment of yeast Atp11p retains full molecular chaperone activity. J Biol Chem. 2003;278:34110-3 pubmed
b>Atp11p is a molecular chaperone of the mitochondrial matrix that participates in the biogenesis pathway to form F1, the catalytic unit of the ATP synthase...