ARO9

Summary

Gene Symbol: ARO9
Description: aromatic-amino-acid:2-oxoglutarate transaminase
Alias: aromatic-amino-acid:2-oxoglutarate transaminase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Pirkov I, Norbeck J, Gustafsson L, Albers E. A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J. 2008;275:4111-20 pubmed publisher
    ..Thus, for the first time, all enzymes of the methionine salvage pathway were identified in a eukaryote. ..
  2. Urrestarazu A, Vissers S, Iraqui I, Grenson M. Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination. Mol Gen Genet. 1998;257:230-7 pubmed
    ..isolation of Saccharomyces cerevisiae mutants lacking aromatic aminotransferase I activity (aro8), and of aro8 and aro9 double mutants which are auxotrophic for both phenylalanine and tyrosine, because the second mutation, aro9 affects ..
  3. Iraqui I, Vissers S, Cartiaux M, Urrestarazu A. Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily. Mol Gen Genet. 1998;257:238-48 pubmed
    The ARO8 and ARO9 genes of Saccharomyces cerevisiae were isolated by complementation of the phenylalanine/tyrosine auxotrophy of an aro8 and aro9 double-mutant strain that is defective in aromatic aminotransferase I (aro8) and II (aro9)...
  4. Iraqui I, Vissers S, Andre B, Urrestarazu A. Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae. Mol Cell Biol. 1999;19:3360-71 pubmed
    Aromatic aminotransferase II, product of the ARO9 gene, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism in Saccharomyces cerevisiae...
  5. Chen H, Huang H, Li X, Tong S, Niu L, Teng M. Crystallization and preliminary X-ray diffraction analysis of ARO9, an aromatic aminotransferase from Saccharomyces cerevisiae. Protein Pept Lett. 2009;16:450-3 pubmed
    Saccharomyces cerevisae ARO9 protein, an aromatic aminotransferase II, catalyzes the transamination step of the catabolism of aromatic amino acids, mainly tryptophan...
  6. Lee K, Sung C, Kim B, Hahn J. Activation of Aro80 transcription factor by heat-induced aromatic amino acid influx in Saccharomyces cerevisiae. Biochem Biophys Res Commun. 2013;438:43-7 pubmed publisher
    In Saccharomyces cerevisiae, transcription of ARO9 and ARO10 genes, involved in the catabolism of aromatic amino acids, is activated by Aro80 transcription factor in response to aromatic amino acids...
  7. Ohashi K, Chaleckis R, Takaine M, Wheelock C, Yoshida S. Kynurenine aminotransferase activity of Aro8/Aro9 engage tryptophan degradation by producing kynurenic acid in Saccharomyces cerevisiae. Sci Rep. 2017;7:12180 pubmed publisher
    ..Amino acid sequence analysis and LC/MS quantification of KA revealed that Aro8 and Aro9 are the major KATs. KA was significantly decreased in the aro8? aro9? double mutant...