ARG8

Summary

Gene Symbol: ARG8
Description: acetylornithine transaminase
Alias: acetylornithine transaminase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Pauwels K, Abadjieva A, Hilven P, Stankiewicz A, Crabeel M. The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis. Eur J Biochem. 2003;270:1014-24 pubmed
    ..We conclude that the NAGS/NAGK metabolon promotes the co-ordination of the catalytic activities and feedback regulation of the first two, flux controlling, enzymes of the arginine pathway. ..
  2. Jauniaux J, Urrestarazu L, Wiame J. Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J Bacteriol. 1978;133:1096-1107 pubmed
  3. Heimberg H, Boyen A, Crabeel M, Glansdorff N. Escherichia coli and Saccharomyces cerevisiae acetylornithine aminotransferase: evolutionary relationship with ornithine aminotransferase. Gene. 1990;90:69-78 pubmed
    Genes argD and ARG8, encoding the acetylornithine aminotransferase (ACOAT) subunit in Escherichia coli and Saccharomyces cerevisiae, respectively, have been cloned and sequenced...
  4. Dujeancourt L, Richter R, Chrzanowska Lightowlers Z, Bonnefoy N, Herbert C. Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria. Mitochondrion. 2013;13:871-80 pubmed publisher
    ..We show that high dosage of Pth4 can compensate for the absence of Mrf1 and loss of Pth4 exacerbates the lack of Mrf1. Also Pth4 is a component of the mitochondrial ribosome, suggesting that it could help recycling stalled ribosomes. ..