Gene Symbol: ARG7
Description: glutamate N-acetyltransferase
Alias: ECM40, glutamate N-acetyltransferase
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Maes D, Crabeel M, Van de Weerdt C, Martial J, Peeters E, Charlier D, et al. Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006;62:1294-7 pubmed
    ..The crystals belong to space group P4, with unit-cell parameters a = b = 66.98, c = 427.09 A, and a data set was collected to 2.76 A. ..
  2. Jauniaux J, Urrestarazu L, Wiame J. Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J Bacteriol. 1978;133:1096-1107 pubmed
  3. Lussier M, White A, Sheraton J, Di Paolo T, Treadwell J, Southard S, et al. Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics. 1997;147:435-50 pubmed
    ..Fifty of these genes were previously known, 17 encoded proteins whose function could be anticipated through sequence homology or previously recognized phenotypes and 15 genes had no previously known phenotype. ..
  4. Crabeel M, Abadjieva A, Hilven P, Desimpelaere J, Soetens O. Characterization of the Saccharomyces cerevisiae ARG7 gene encoding ornithine acetyltransferase, an enzyme also endowed with acetylglutamate synthase activity. Eur J Biochem. 1997;250:232-41 pubmed
    We have cloned by functional complementation and characterized the yeast ARG7 gene encoding mitochondrial ornithine acetyltransferase, the enzyme catalyzing the fifth step in arginine biosynthesis...
  5. Pauwels K, Abadjieva A, Hilven P, Stankiewicz A, Crabeel M. The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis. Eur J Biochem. 2003;270:1014-24 pubmed
    ..We conclude that the NAGS/NAGK metabolon promotes the co-ordination of the catalytic activities and feedback regulation of the first two, flux controlling, enzymes of the arginine pathway. ..