Genomes and Genes
Gene Symbol: ARE2
Description: sterol acyltransferase
Alias: SAT1, sterol acyltransferase
Species: Saccharomyces cerevisiae S288c
- Klein I, Klug L, Schmidt C, Zandl M, Korber M, Daum G, et al. Regulation of the yeast triacylglycerol lipases Tgl4p and Tgl5p by the presence/absence of nonpolar lipids. Mol Biol Cell. 2016;27:2014-24 pubmed publisher..These results suggest that Tgl3p, Tgl4p, and Tgl5p, although they exhibit similar functions, act as independent entities. ..
- Sandager L, Gustavsson M, Stahl U, Dahlqvist A, Wiberg E, Banas A, et al. Storage lipid synthesis is non-essential in yeast. J Biol Chem. 2002;277:6478-82 pubmed..We have used single and multiple gene disruptions to study storage lipid synthesis in yeast. Four genes, ARE1, ARE2, DGA1, and LRO1, were found to contribute to TAG synthesis...
- Hodge C, Choudhary V, Wolyniak M, Scarcelli J, Schneiter R, Cole C. Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci. 2010;123:141-51 pubmed publisher..These data indicate that Brr6 has an essential function in regulating lipid homeostasis in the NE-ER, thereby impacting NPC formation and nucleocytoplasmic transport. ..
- Foresti O, Ruggiano A, Hannibal Bach H, Ejsing C, Carvalho P. Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4. elife. 2013;2:e00953 pubmed publisher..DOI:http://dx.doi.org/10.7554/eLife.00953.001. ..
- Lone M, Atkinson A, Hodge C, Cottier S, MartÃnez MontaÃ±Ã©s F, Maithel S, et al. Yeast Integral Membrane Proteins Apq12, Brl1, and Brr6 Form a Complex Important for Regulation of Membrane Homeostasis and Nuclear Pore Complex Biogenesis. Eukaryot Cell. 2015;14:1217-27 pubmed publisher..We suggest that the defects in nuclear pore complex biogenesis and mRNA export seen in these mutants are consequences of defects in maintaining the biophysical properties of the NE. ..
- Jacquier N, Choudhary V, Mari M, Toulmay A, Reggiori F, Schneiter R. Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Sci. 2011;124:2424-37 pubmed publisher..These observations indicate that LDs are functionally connected to the ER membrane and that this connection allows the efficient partitioning of membrane proteins between the two compartments. ..