ALT1

Summary

Gene Symbol: ALT1
Description: alanine transaminase ALT1
Alias: alanine transaminase ALT1
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. García Campusano F, Anaya V, Robledo Arratia L, Quezada H, Hernández H, Riego L, et al. ALT1-encoded alanine aminotransferase plays a central role in the metabolism of alanine in Saccharomyces cerevisiae. Can J Microbiol. 2009;55:368-74 pubmed publisher
    In the yeast Saccharomyces cerevisiae, the paralogous genes ALT1 and ALT2 have been proposed to encode alanine aminotransferase isozymes...
  2. Peñalosa Ruiz G, Aranda C, Ongay Larios L, Colón M, Quezada H, Gonzalez A. Paralogous ALT1 and ALT2 retention and diversification have generated catalytically active and inactive aminotransferases in Saccharomyces cerevisiae. PLoS ONE. 2012;7:e45702 pubmed publisher
    ..S. cerevisiae possesses two paralogous genes (ALT1/ALT2) which presumably encode alanine aminotransferases...
  3. Yu S, An Y, Yang H, Kang M, Kim H, Wen H, et al. Alanine-metabolizing enzyme Alt1 is critical in determining yeast life span, as revealed by combined metabolomic and genetic studies. J Proteome Res. 2013;12:1619-27 pubmed publisher
    ..The involvement of the alanine-metabolizing pathway in the life span was tested using a deletion mutant of ALT1, the gene for a key alanine-metabolizing enzyme...
  4. Nishida I, Watanabe D, Takagi H. Putative mitochondrial ?-ketoglutarate-dependent dioxygenase Fmp12 controls utilization of proline as an energy source in Saccharomyces cerevisiae. Microb Cell. 2016;3:522-528 pubmed publisher
    ..i>PUT1), ?1-pyrroline-5-carboxylate dehydrogenase (PUT2), alanine transaminase (ALT1), and ?-ketoglutarate dehydrogenase subunit (KGD1), abolished the enhanced cell growth in ?fmp12...
  5. Grandier Vazeille X, Bathany K, Chaignepain S, Camougrand N, Manon S, Schmitter J. Yeast mitochondrial dehydrogenases are associated in a supramolecular complex. Biochemistry. 2001;40:9758-69 pubmed
    ..The association of these proteins is discussed in terms of NADH-channeling. ..