Gene Symbol: AGA1
Description: Aga1p
Alias: Aga1p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Roy A, Lu C, Marykwas D, Lipke P, Kurjan J. The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin. Mol Cell Biol. 1991;11:4196-206 pubmed
    ..agglutination defects were isolated, the majority of which fell into a single complementation group, called aga1. The aga1 mutants showed wild-type pheromone production and response, efficient mating on solid medium, and a ..
  2. Cappellaro C, Baldermann C, Rachel R, Tanner W. Mating type-specific cell-cell recognition of Saccharomyces cerevisiae: cell wall attachment and active sites of a- and alpha-agglutinin. EMBO J. 1994;13:4737-44 pubmed bound via two S-S bridges (Cys7 and Cys50) to a cell wall component, most probably the gene product of AGA1. His273 of alpha-agglutinin has previously been shown to be essential for a- and alpha-agglutinin interaction and a ..
  3. Zhao H, Shen Z, Kahn P, Lipke P. Interaction of alpha-agglutinin and a-agglutinin, Saccharomyces cerevisiae sexual cell adhesion molecules. J Bacteriol. 2001;183:2874-80 pubmed
    ..An induced-fit model of binding with substantial apposition of hydrophobic surfaces on the two ligands can explain the observed affinity, kinetics, and specificity and the conformational effects of the binding reaction. ..
  4. Frýdlová I, Basler M, Vasicová P, Malcová I, Hasek J. Special type of pheromone-induced invasive growth in Saccharomyces cerevisiae. Curr Genet. 2007;52:87-95 pubmed
    ..We show here that another pheromone-induced protein, mating agglutinin Aga1p, can play a role in the agar adhesion necessary for invasion...
  5. Huang G, Dougherty S, Erdman S. Conserved WCPL and CX4C domains mediate several mating adhesin interactions in Saccharomyces cerevisiae. Genetics. 2009;182:173-89 pubmed publisher
    Several adhesins are induced by pheromones during mating in Saccharomyces cerevisiae, including Aga1p, Aga2p, Sag1p (Agalpha1p), and Fig2p...
  6. Hirschmann W, Westendorf H, Mayer A, Cannarozzi G, Cramer P, Jansen R. Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Res. 2014;42:4043-55 pubmed publisher
    ..Our data indicate that Scp160p might increase the efficiency of tRNA recharge, or prevent diffusion of discharged tRNAs, both of which were also proposed to be the likely basis for the translational fitness effect of tRNA pairing...