ACO2

Summary

Gene Symbol: ACO2
Description: aconitate hydratase ACO2
Alias: aconitate hydratase ACO2
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Tatusov R, Galperin M, Natale D, Koonin E. The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res. 2000;28:33-6 pubmed
    ..The COG database is accompanied by the COGNITOR program that is used to fit new proteins into the COGs and can be applied to functional and phylogenetic annotation of newly sequenced genomes. ..
  2. Fazius F, Shelest E, Gebhardt P, Brock M. The fungal ?-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate. Mol Microbiol. 2012;86:1508-30 pubmed publisher
  3. Melber A, Na U, Vashisht A, Weiler B, Lill R, Wohlschlegel J, et al. Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients. elife. 2016;5: pubmed publisher
    ..Given these observations, we propose that Nfu1, assisted by Bol3, functions to facilitate Fe-S transfer from the biosynthetic apparatus to the client proteins preventing oxidative damage to [4Fe-4S] clusters. ..