ABZ2

Summary

Gene Symbol: ABZ2
Description: aminodeoxychorismate lyase ABZ2
Alias: aminodeoxychorismate lyase ABZ2
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. Botet J, Mateos L, Revuelta J, Santos M. A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase. Eukaryot Cell. 2007;6:2102-11 pubmed
    ..In light of these results, YMR289w was designated ABZ2, in accordance with the accepted nomenclature...
  2. Dai Y, Chi C, Zhou K, Cheng W, Jiang Y, Ren Y, et al. Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase. J Biol Chem. 2013;288:22985-92 pubmed publisher
    Saccharomyces cerevisiae Abz2 is a pyridoxal 5'-phosphate (PLP)-dependent lyase that converts 4-amino-4-deoxychorismate (ADC) to para-aminobenzoate and pyruvate. To investigate the catalytic mechanism, we determined the 1...