Research Topics
| rpsMSummaryGene Symbol: rpsM Description: 30S ribosomal protein S13 Species: Top Publications
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Detail Information
Publications
Cloning of the RNA polymerase alpha subunit gene from Thermus thermophilus HB8 and characterization of the proteinT Wada
Institute for Protein Research, Osaka University, Suita, Osaka, 565 0871, Japan
J Biochem 125:143-50. 1999..By means of a T7-based expression system in Ec cells, Tt RNAPalpha was overexpressed and purified. The high thermostability of Tt RNAPalpha was demonstrated by the CD spectra...
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunitD E Brodersen
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
Cell 103:1143-54. 2000..For each of these antibiotics, interactions with the 30S subunit suggest a mechanism for its effects on ribosome function...
Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolutionF Schluenzen
Max-Planck-Research Unit for Ribosomal Structure, Hamburg, Germany
Cell 102:615-23. 2000..96% of the nucleotides were traced and the main fold of all proteins was determined. The latter are either peripheral or appear to serve as linkers. Some may assist the directionality of translocation...
Structure of the 30S ribosomal subunitB T Wimberly
MRC Laboratory of Molecular Biology, Cambridge, UK
Nature 407:327-39. 2000..The structure will facilitate the interpretation in molecular terms of lower resolution structural data on several functional states of the ribosome from electron microscopy and crystallography...
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibioticsA P Carter
MRC Laboratory of Molecular Biology, Cambridge, UK
Nature 407:340-8. 2000..This work reveals the structural basis for the action of these antibiotics, and leads to a model for the role of the universally conserved 16S RNA residues A1492 and A1493 in the decoding process...
Crystal structure of the ribosome at 5.5 A resolutionM M Yusupov
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California at Santa Cruz, Santa Cruz, CA 95064, USA
Science 292:883-96. 2001..The tRNAs are closely juxtaposed with the intersubunit bridges, in a way that suggests coupling of the 20 to 50 angstrom movements associated with tRNA translocation with intersubunit movement...
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3M Pioletti
Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, 14195 Berlin, Germany
EMBO J 20:1829-39. 2001....
Recognition of cognate transfer RNA by the 30S ribosomal subunitJ M Ogle
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
Science 292:897-902. 2001..The third, or "wobble," position of the codon is free to accommodate certain noncanonical base pairs. By partially inducing these structural changes, paromomycin facilitates binding of near-cognate tRNAs...
The path of messenger RNA through the ribosomeG Z Yusupova
Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California-Santa Cruz, Santa Cruz, CA 95064, USA
Cell 106:233-41. 2001..The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting...
