DRD2

Summary

Gene Symbol: DRD2
Description: dopamine receptor D2
Species: Rhesus monkey

Top Publications

  1. pmc Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI
    Christin Y Sander
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 110:11169-74. 2013
  2. ncbi Distribution of dopamine D1, D2, and D5 receptor mRNAs in the monkey brain: ribonuclease protection assay analysis
    W S Choi
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Brain Res Mol Brain Res 31:86-94. 1995
  3. ncbi PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys
    Michael A Nader
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    Nat Neurosci 9:1050-6. 2006

Scientific Experts

  • Michael Nader
  • Christin Y Sander
  • Nathaniel M Alpert
  • Ciprian Catana
  • Gitte M Knudsen
  • Jacob M Hooker
  • Wim Vanduffel
  • Joseph B Mandeville
  • Marc D Normandin
  • Bruce R Rosen
  • W S Choi
  • O K Ronnekleiv
  • C A Machida

Detail Information

Publications3

  1. pmc Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI
    Christin Y Sander
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 110:11169-74. 2013
    ..Overall, these data demonstrate the utility of simultaneous PET/fMRI for investigations of neurovascular coupling that correlate neurochemistry with hemodynamic changes in vivo for any receptor system with an available PET tracer. ..
  2. ncbi Distribution of dopamine D1, D2, and D5 receptor mRNAs in the monkey brain: ribonuclease protection assay analysis
    W S Choi
    Division of Neuroscience, Oregon Regional Primate Research Center, Beaverton 97006, USA
    Brain Res Mol Brain Res 31:86-94. 1995
    ..The D5 receptor mRNA appears to be widely distributed in the monkey brain. Most interesting is the expression of D5 receptor mRNA in tissues of the substantia nigra area...
  3. ncbi PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys
    Michael A Nader
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    Nat Neurosci 9:1050-6. 2006
    ..Individual differences in the rate of recovery of D2 receptor function during abstinence were noted...

Research Grants29

  1. Transition to Cocaine Abuse in Monkey:Role of Dopamine
    Michael Nader; Fiscal Year: 2005
    ....
  2. Chronic Stress and Cocaine Abuse in Female Monkeys
    Michael Nader; Fiscal Year: 2007
    ....
  3. Social Stress: Vulnerability to Cocaine Abuse in Monkeys
    Michael Nader; Fiscal Year: 2007
    ..Such information will lead to better treatment and prevention strategies. ..
  4. Impact of In Utero Cocaine Exposure on Vulnerability to Drug Abuse in Monkeys.
    Michael Nader; Fiscal Year: 2009
    ..These studies will further explore factors related to etiology and maintenance of drug abuse, which should aid in the development of novel treatment strategies. ..
  5. Impact of In Utero Cocaine Exposure on Vulnerability to Drug Abuse in Monkeys.
    Michael A Nader; Fiscal Year: 2010
    ..These studies will further explore factors related to etiology and maintenance of drug abuse, which should aid in the development of novel treatment strategies. ..
  6. DOPAMINE D2 RECEPTORS IN PRIMATE MODELS OF COCAINE ABUSE
    Michael Nader; Fiscal Year: 2004
    ..Such knowledge will be vital for understanding the neuropharmacology of cocaine and to the development of effective pharmacotherapies for cocaine abuse. ..
  7. SOCIAL STRESS--VULNERABILITY TO COCAINE ABUSE
    Michael Nader; Fiscal Year: 1999
    ..A better understanding of the variables that contribute to enhanced sensitivity to the reinforcing effects of cocaine may lead to better behavioral and/or pharmacological strategies for the treatment and prevention of cocaine abuse. ..
  8. DOPAMINE D2 RECEPTORS IN PRIMATE MODELS OF COCAINE ABUSE
    Michael A Nader; Fiscal Year: 2010
    ....