Gene Symbol: M
Description: Matrix protein (M)
Species: Respiratory syncytial virus
Ghildyal R, Ho A, Wagstaff K, Dias M, Barton C, Jans P, et al
. Nuclear import of the respiratory syncytial virus matrix protein is mediated by importin beta1 independent of importin alpha. Biochemistry. 2005;44:12887-95 pubmed
The matrix (M) protein of respiratory syncytial virus (RSV) plays an important role in virus assembly through specific interactions with RSV nucleocapsids and envelope glycoproteins in the cytoplasm as well as with the host cell membrane...
Ghildyal R, Ho A, Dias M, Soegiyono L, Bardin P, Tran K, et al
. The respiratory syncytial virus matrix protein possesses a Crm1-mediated nuclear export mechanism. J Virol. 2009;83:5353-62 pubmed publisher
The respiratory syncytial virus (RSV) matrix (M) protein is localized in the nucleus of infected cells early in infection but is mostly cytoplasmic late in infection...
Tolley K, Marriott A, Simpson A, Plows D, Matthews D, Longhurst S, et al
. Identification of mutations contributing to the reduced virulence of a modified strain of respiratory syncytial virus. Vaccine. 1996;14:1637-46 pubmed
..The data suggest also that a mutation in the F gene may contribute to the attenuated phenotype. ..
Ghildyal R, Li D, Peroulis I, Shields B, Bardin P, Teng M, et al
. Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein. J Gen Virol. 2005;86:1879-84 pubmed publisher
..Here, the postulated interaction between the RSV matrix protein (M) and G glycoprotein (G) was investigated...
Li D, Jans D, Bardin P, Meanger J, Mills J, Ghildyal R. Association of respiratory syncytial virus M protein with viral nucleocapsids is mediated by the M2-1 protein. J Virol. 2008;82:8863-70 pubmed publisher
..Although not believed to be necessary for transcription, the matrix (M) protein is also present in these inclusions, and we have previously shown that M inhibits viral transcription...
Money V, McPhee H, Mosely J, Sanderson J, Yeo R. Surface features of a Mononegavirales matrix protein indicate sites of membrane interaction. Proc Natl Acad Sci U S A. 2009;106:4441-6 pubmed publisher
The matrix protein (M) of respiratory syncytial virus (RSV), the prototype viral member of the Pneumovirinae (family Paramyxoviridae, order Mononegavirales), has been crystallized and the structure determined to a resolution of 1.6 A...
Bian T, Gibbs J, rvell C, Imani F. Respiratory syncytial virus matrix protein induces lung epithelial cell cycle arrest through a p53 dependent pathway. PLoS ONE. 2012;7:e38052 pubmed publisher
..To address the mechanism of RSV-induced cell cycle arrest, we examined the contribution of RSV-matrix (RSV-M) protein...
Bajorek M, Caly L, Tran K, Maertens G, Tripp R, Bacharach E, et al
. The Thr205 phosphorylation site within respiratory syncytial virus matrix (M) protein modulates M oligomerization and virus production. J Virol. 2014;88:6380-93 pubmed publisher
..The RSV matrix (M) protein plays key roles in virus assembly and budding, but the protein interactions that govern budding of ..