Gene Symbol: LOC657528
Description: dihydrolipoyl dehydrogenase, mitochondrial
Alias: dld, dihydrolipoyl dehydrogenase, mitochondrial, AUGUSTUS-3.0.2_06823, AUGUSTUS-3.0.2_34990, Dihydrolipoyl dehydrogenase, mitochondrial -like protein, Dihydrolipoyl dehydrogenase-like Protein, GLEAN_06822, GLEAN_06823, dihydrolipoamide dehydrogenase E3 subunit, dihydrolipoamide dehydrogenase phosphine resistant, dihydrolipoyl dehydrogenase, mitochondrial pseudogene
Species: red flour beetle

Top Publications

  1. Schlipalius D, Valmas N, Tuck A, Jagadeesan R, Ma L, Kaur R, et al. A core metabolic enzyme mediates resistance to phosphine gas. Science. 2012;338:807-10 pubmed publisher
    ..around the redox-active catalytic disulfide or the dimerization interface of dihydrolipoamide dehydrogenase (DLD) in insects (Rhyzopertha dominica and Tribolium castaneum) and nematodes (Caenorhabditis elegans)...
  2. Jagadeesan R, Fotheringham A, Ebert P, Schlipalius D. Rapid genome wide mapping of phosphine resistance loci by a simple regional averaging analysis in the red flour beetle, Tribolium castaneum. BMC Genomics. 2013;14:650 pubmed publisher
    ..castaneum. This is a relatively simple and rapid approach to identifying genomic regions associated with traits in defined genetic crosses that does not require any specialised statistical analysis. ..
  3. Kaur R, Subbarayalu M, Jagadeesan R, Daglish G, Nayak M, Naik H, et al. Phosphine resistance in India is characterised by a dihydrolipoamide dehydrogenase variant that is otherwise unobserved in eukaryotes. Heredity (Edinb). 2015;115:188-94 pubmed publisher
    ..Sequencing analysis of the rph2 locus, dihydrolipoamide dehydrogenase (dld), identified two structurally equivalent variants, Proline49>Serine (P49S) in one R...