Research Topics

Species

Gene Symbol: LOC656158

Description: toll-like receptor 3

Alias: Toll3, protein toll, AUGUSTUS-3.0.2_04438, GLEAN_04438, toll-like protein

Species: red flour beetle

Zou Z, Evans J, Lu Z, Zhao P, Williams M, Sumathipala N, et al. Comparative genomic analysis of the Tribolium immune system. Genome Biol. 2007;8:R177 pubmed publisher

..A framework of information on Tribolium immunity is established, which may serve as a stepping stone for future genetic analyses of defense responses in a nondrosophiline genetic model insect...
Shrestha S, Kim Y. Activation of immune-associated phospholipase A2 is functionally linked to Toll/Imd signal pathways in the red flour beetle, Tribolium castaneum. Dev Comp Immunol. 2010;34:530-7 pubmed publisher

..These results suggest that recognition of bacterial challenge initiates Toll and Imd pathways in T. castaneum, which subsequently induces the activation of immune-associated PLA(2)s as well as gene expression of various AMPs...