Znhit1

Summary

Gene Symbol: Znhit1
Description: zinc finger, HIT-type containing 1
Alias: zinc finger HIT domain-containing protein 1, zinc finger, HIT domain containing 1
Species: rat
Products:     Znhit1

Top Publications

  1. Wang J, Li Y, Zhang M, Liu Z, Wu C, Yuan H, et al. A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription. FEBS J. 2007;274:5370-81 pubmed
    ..These findings demonstrate that ZNHIT-1 functions as a cofactor to regulate the activity of Rev-erbbeta, and may play a role in lipid metabolism. ..
  2. Yang Z, Cao Y, Zhu X, Huang Y, Ding Y, Liu X. Znhit1 causes cell cycle arrest and down-regulates CDK6 expression. Biochem Biophys Res Commun. 2009;386:146-52 pubmed publisher
    ..In this study, Znhit1, a member of a new zinc finger protein family defined by a conserved Zf-HIT domain, induced arrest in the G1-phase ..
  3. Beckerman R, Prives C. Transcriptional regulation by p53. Cold Spring Harb Perspect Biol. 2010;2:a000935 pubmed publisher
    ..How p53 is able to discriminate between these different loci is the subject of intense research. Here, we describe key aspects of the fundamentals of p53-mediated transcriptional regulation and target gene promoter selectivity. ..