Tomm7

Summary

Gene Symbol: Tomm7
Description: translocase of outer mitochondrial membrane 7
Alias: mitochondrial import receptor subunit TOM7 homolog
Species: rat
Products:     Tomm7

Top Publications

  1. Wu H, Chen Q. Hypoxia activation of mitophagy and its role in disease pathogenesis. Antioxid Redox Signal. 2015;22:1032-46 pubmed publisher
    ..An improved understanding of the regulation of mitochondrial quality may provide a strategy for treating aging-related diseases by targeting mitochondria and mitophagy pathways. ..
  2. Wenz L, OpaliÅ„ski Å, Wiedemann N, Becker T. Cooperation of protein machineries in mitochondrial protein sorting. Biochim Biophys Acta. 2015;1853:1119-29 pubmed publisher
    ..Therefore, we propose that the protein transport systems are part of a complicated protein network for mitochondrial biogenesis. ..
  3. Höhr A, Straub S, Warscheid B, Becker T, Wiedemann N. Assembly of β-barrel proteins in the mitochondrial outer membrane. Biochim Biophys Acta. 2015;1853:74-88 pubmed publisher
  4. Johnston A, Hoogenraad J, Dougan D, Truscott K, Yano M, Mori M, et al. Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane. J Biol Chem. 2002;277:42197-204 pubmed
    ..These results indicate that the levels of Tom22 within mitochondria dictate the assembly of TOM complexes and hence may regulate its biogenesis. ..
  5. Schulz C, Schendzielorz A, Rehling P. Unlocking the presequence import pathway. Trends Cell Biol. 2015;25:265-75 pubmed publisher
    ..Here, we review recent advances in understanding of the mechanisms underlying protein transport along the presequence pathway. ..
  6. Ellenrieder L, MÃ¥rtensson C, Becker T. Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Biol Chem. 2015;396:1199-213 pubmed publisher
    ..We summarize current models and open questions of biogenesis of mitochondrial outer membrane proteins and discuss the impact of malfunctions of protein sorting on the development of diseases. ..