Tmc6

Summary

Gene Symbol: Tmc6
Description: transmembrane channel like 6
Species: rat
Products:     Tmc6

Top Publications

  1. Ramoz N, Rueda L, Bouadjar B, Montoya L, Orth G, Favre M. Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis. Nat Genet. 2002;32:579-81 pubmed
    ..The gene products EVER1 and EVER2 have features of integral membrane proteins and are localized in the endoplasmic reticulum...
  2. Lazarczyk M, Pons C, Mendoza J, Cassonnet P, Jacob Y, Favre M. Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses. J Exp Med. 2008;205:35-42 pubmed
    ..HPV16 E5 protein binds to EVER and ZnT-1 and blocks their negative regulation. The lack of a functional E5 protein encoded by EV HPV genome may account for host restriction of these viruses...