Timm10

Summary

Gene Symbol: Timm10
Description: translocase of inner mitochondrial membrane 10
Alias: Tim10, mitochondrial import inner membrane translocase subunit Tim10, small zinc finger-like protein, translocase of inner mitochondrial membrane 10 homolog
Species: rat
Products:     Timm10

Top Publications

  1. Adrian G, McCammon M, Montgomery D, Douglas M. Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol Cell Biol. 1986;6:626-34 pubmed
    ..These results are discussed in light of the function of distinct protein elements at the amino terminus of mitochondrially destined precursors in both organelle delivery and correct membrane localization. ..
  2. Bauer M, Rothbauer U, Mühlenbein N, Smith R, Gerbitz K, Neupert W, et al. The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom. FEBS Lett. 1999;464:41-7 pubmed
    ..DDP1 shows similarity to the yeast proteins Tim9, Tim10 and Tim12, components of the mitochondrial import machinery for carrier proteins...
  3. Mühlenbein N, Hofmann S, Rothbauer U, Bauer M. Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria. J Biol Chem. 2004;279:13540-6 pubmed
    ..We conclude that different mechanisms and specific requirements for import and insertion of mammalian carrier preproteins have evolved in higher eukaryotes. ..
  4. Webb C, Gorman M, Lazarou M, Ryan M, Gulbis J. Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller. Mol Cell. 2006;21:123-33 pubmed
    ..Tim9 and Tim10 are translocase components of the intermembrane space, related to deafness-dystonia peptide 1 (DDP1)...
  5. Höhr A, Straub S, Warscheid B, Becker T, Wiedemann N. Assembly of β-barrel proteins in the mitochondrial outer membrane. Biochim Biophys Acta. 2015;1853:74-88 pubmed publisher