Gene Symbol: Tec
Description: tec protein tyrosine kinase
Alias: tyrosine-protein kinase Tec, cytoplasmic tyrosine kinase, Dscr28C related
Species: rat
Products:     Tec

Top Publications

  1. Laffargue M, Monnereau L, Tuech J, Ragab A, Ragab Thomas J, Payrastre B, et al. Integrin-dependent tyrosine phoshorylation and cytoskeletal translocation of Tec in thrombin-activated platelets. Biochem Biophys Res Commun. 1997;238:247-51 pubmed
    Using a specific polyclonal anti-Tec antibody, we have shown that Tec is expressed in human platelets. In addition, Tec was found to undergo tyrosine phosphorylation during platelet activation...
  2. Hamazaki Y, Kojima H, Mano H, Nagata Y, Todokoro K, Abe T, et al. Tec is involved in G protein-coupled receptor- and integrin-mediated signalings in human blood platelets. Oncogene. 1998;16:2773-9 pubmed
    b>Tec is a non-receptor type tyrosine kinase which is tyrosine phosphorylated and activated upon stimulation of hematopoietic cells with various cytokines...
  3. Ohya K, Kajigaya S, Kitanaka A, Yoshida K, Miyazato A, Yamashita Y, et al. Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase. Proc Natl Acad Sci U S A. 1999;96:11976-81 pubmed
    b>Tec, Btk, Itk, Bmx, and Txk constitute the Tec family of protein tyrosine kinases (PTKs), a family with the distinct feature of containing a pleckstrin homology (PH) domain...
  4. Xu W, Wang S, Wang G, Wei H, He F, Yang X. Identification and characterization of differentially expressed genes in the early response phase during liver regeneration. Biochem Biophys Res Commun. 2000;278:318-25 pubmed
    ..PC3 and TEC genes were identified as immediate-early response genes and were dramatically increased following partial ..
  5. Li F, Jiang Y, Zheng Q, Yang X, Wang S. TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF. Biochem Biophys Res Commun. 2011;404:79-85 pubmed publisher
    b>TEC, a member of the TEC family of non-receptor type protein tyrosine kinases, has recently been suggested to play a role in hepatocyte proliferation and liver regeneration...