Gene Symbol: St3gal2
Description: ST3 beta-galactoside alpha-2,3-sialyltransferase 2
Alias: Siat4b, Siat5, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2, SIAT4-B, ST3GALA.2, ST3Gal II, ST3GalII, alpha 2,3-ST 2, beta-galactoside alpha-2,3-sialyltransferase 2, gal-NAc6S, gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase, sialyltransferase 4B (beta-galactoside alpha-2,3-sialyltransferase), sialyltransferase 5
Species: rat
Products:     St3gal2

Top Publications

  1. Kono M, Ohyama Y, Lee Y, Hamamoto T, Kojima N, Tsuji S. Mouse beta-galactoside alpha 2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression. Glycobiology. 1997;7:469-79 pubmed
    ..The ST3Gal II gene was strongly expressed in brain, and weakly in colon, thymus, salivary gland, and testis, and ..
  2. Giordanengo V, Bannwarth S, Laffont C, Van Miegem V, Harduin Lepers A, Delannoy P, et al. Cloning and expression of cDNA for a human Gal(beta1-3)GalNAc alpha2,3-sialyltransferase from the CEM T-cell line. Eur J Biochem. 1997;247:558-66 pubmed
    ..amp; Paulson, J. C. (1994) J. Biol. Chem. 269, 17872-17878] and 88.1% and 93.7% similarity to murine ST3Gal II [Lee, Y. C., Kojima, N., Wada, E., Kurosawa, N., Nakaoka, T., Hamamoto, T. & Tsuji, S. (1994) J. Biol. Chem...
  3. Chandrasekaran E, Xue J, Xia J, Locke R, Patil S, Neelamegham S, et al. Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides. Biochemistry. 2011;50:9475-87 pubmed publisher
    ..This technique has the potential to serve as an important tool as it provides a natural tag for the chemical and functional characterization of O-glycan-bearing glycoproteins. ..
  4. Lee Y, Kojima N, Wada E, Kurosawa N, Nakaoka T, Hamamoto T, et al. Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase. J Biol Chem. 1994;269:10028-33 pubmed
    ..1, but showed a difference in acceptor substrate preference, i.e. asialo-GM1 and GM1 were much more suitable substrates for ST3GalA.2 than for ST3GalA.1. ..