Slc39a6

Summary

Gene Symbol: Slc39a6
Description: solute carrier family 39 member 6
Alias: zinc transporter ZIP6, ZIP-6, solute carrier family 39 (metal ion transporter), member 6, solute carrier family 39 (zinc transporter), member 6, zrt- and Irt-like protein 6
Species: rat
Products:     Slc39a6

Top Publications

  1. Suzuki A, Endo T. Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes. Gene. 2002;284:31-40 pubmed
    ..These results suggest that at least some, if not all, of the HELP domain-containing proteins are multipass endoplasmic reticulum membrane proteins with functions conserved among eukaryotes. ..
  2. Taylor K, Morgan H, Johnson A, Hadley L, Nicholson R. Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. Biochem J. 2003;375:51-9 pubmed
    ..Combining the crucial role that zinc plays in cell growth and the proven role of metalloproteases in metastasis presents an exciting indication of how LIV-1 plays a role in breast cancer progression. ..
  3. Taylor K, Morgan H, Johnson A, Nicholson R. Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14. FEBS Lett. 2005;579:427-32 pubmed
    ..We demonstrate that this plasma membrane located glycosylated protein functions as a zinc influx transporter in a temperature-dependant manner. ..
  4. Chowanadisai W, Kelleher S, Lonnerdal B. Zinc deficiency is associated with increased brain zinc import and LIV-1 expression and decreased ZnT-1 expression in neonatal rats. J Nutr. 2005;135:1002-7 pubmed
    ..Our results indicate that Zn deficiency results in alterations in Zn transporter expression, which facilitates increased brain Zn uptake and results in the conservation of brain Zn during Zn deficiency. ..