Slc30a7

Summary

Gene Symbol: Slc30a7
Description: solute carrier family 30 member 7
Alias: zinc transporter 7, solute carrier family 30 (zinc transporter), member 7, znT-7
Species: rat
Products:     Slc30a7

Top Publications

  1. Tian T, Li L, Zhang S, Ni H. Long-Term Effects of Ketogenic Diet on Subsequent Seizure-Induced Brain Injury During Early Adulthood: Relationship of Seizure Thresholds to Zinc Transporter-Related Gene Expressions. Biol Trace Elem Res. 2016;174:369-376 pubmed
  2. Tuncay E, Bitirim V, Durak A, Carrat G, Taylor K, Rutter G, et al. Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart. Diabetes. 2017;66:1346-1358 pubmed publisher
    ..We conclude that subcellular free Zn2+ redistribution in the hyperglycemic heart, resulting from altered ZIP7 and ZnT7 activity, contributes to cardiac dysfunction in diabetes. ..
  3. Kirschke C, Huang L. ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus. J Biol Chem. 2003;278:4096-102 pubmed
    ..Exposure of the ZnT7-expressing Chinese hamster ovary (CHO) cells to zinc causes an accumulation of zinc in the Golgi apparatus, suggesting that ZnT7 facilitates zinc transport from the cytoplasm into the Golgi apparatus. ..
  4. Falcon Perez J, Dell Angelica E. Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes. Exp Cell Res. 2007;313:1473-83 pubmed
  5. Zhang L, Chi Z, Ren H, Rong M, Dahlstrom A, Huang L, et al. Imunoreactivity of zinc transporter 7 (ZNT7) in mouse dorsal root ganglia. Brain Res Bull. 2007;74:278-83 pubmed
    ..These observations strongly suggest that ZNT7 may play an important role in facilitating zinc transport into the Golgi apparatus from the cytosol in the mouse DRG. ..
  6. Zhang X, Liang D, Guo B, Sun L, Chi Z, Cai Y, et al. Zinc transporter 7 induced by high glucose attenuates epithelial-to-mesenchymal transition of peritoneal mesothelial cells. Biol Trace Elem Res. 2013;151:138-47 pubmed publisher
    ..We explored ZnT7 (Slc30A7): the effect of ZnT7 over-expression and siRNA-mediated knock-down on HG-induced EMT was investigated as well as ..