Slc22a16

Summary

Gene Symbol: Slc22a16
Description: solute carrier family 22 member 16
Alias: LOW QUALITY PROTEIN: solute carrier family 22 member 16, solute carrier family 22 member 16, solute carrier family 22 (organic cation/carnitine transporter), member 16
Species: rat

Top Publications

  1. Enomoto A, Wempe M, Tsuchida H, Shin H, Cha S, Anzai N, et al. Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. J Biol Chem. 2002;277:36262-71 pubmed
    ..The identification of CT2 represents an interesting evolutionary link between OCT/OCTNs and OATs, as well as provides us with an important insight into the maturation of human spermatozoa. ..
  2. Okabe M, Unno M, Harigae H, Kaku M, Okitsu Y, Sasaki T, et al. Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. Biochem Biophys Res Commun. 2005;333:754-62 pubmed
    ..We report the expression profile and pharmacological characterization of an organic cation transporter, SLC22A16. The results of our experiments indicate that SLC22A16 is a mediator of doxorubicin uptake in cancer cells...
  3. Thorn C, Oshiro C, Marsh S, Hernandez Boussard T, McLeod H, Klein T, et al. Doxorubicin pathways: pharmacodynamics and adverse effects. Pharmacogenet Genomics. 2011;21:440-6 pubmed publisher