Slc13a1

Summary

Gene Symbol: Slc13a1
Description: solute carrier family 13 member 1
Alias: solute carrier family 13 member 1, Na(+)/sulfate cotransporter, naSi-1, renal sodium/sulfate cotransporter, solute carrier family 13 (sodium/sulfate symporter), member 1, solute carrier family 13 (sodium/sulfate symporters), member 1, solute carrier family 13 (sodium/sulphate symporters), member 1
Species: rat

Top Publications

  1. Markovich D, Forgo J, Stange G, Biber J, Murer H. Expression cloning of rat renal Na+/SO4(2-) cotransport. Proc Natl Acad Sci U S A. 1993;90:8073-7 pubmed
    ..The above data indicate that we have structurally identified a membrane protein involved in renal and small-intestinal brush-border membrane Na+/SO4(2-) cotransport. ..
  2. Regeer R, Nicke A, Markovich D. Quaternary structure and apical membrane sorting of the mammalian NaSi-1 sulfate transporter in renal cell lines. Int J Biochem Cell Biol. 2007;39:2240-51 pubmed
    ..Our data demonstrates that NaSi-1 forms a dimeric protein which is glycosylated at N591, whose sorting to the apical membrane in renal epithelial cells is brefeldin A-sensitive and independent of lipid rafts or glycosylation. ..
  3. Norbis F, Perego C, Markovich D, Stange G, Verri T, Murer H. cDNA cloning of a rat small-intestinal Na+/SO4(2-) cotransporter. Pflugers Arch. 1994;428:217-23 pubmed
    ..It differs to the renal NaSi-1 only in the length of the 3' untranslated region, suggesting that the major difference lies in the differential use of polyadenylation signals. ..
  4. Beck L, Markovich D. The mouse Na(+)-sulfate cotransporter gene Nas1. Cloning, tissue distribution, gene structure, chromosomal assignment, and transcriptional regulation by vitamin D. J Biol Chem. 2000;275:11880-90 pubmed
    ..It also provides the basis for a detailed analysis of Nas1 gene regulation and the tools required for assessing Nas1 role in sulfate homeostasis using targeted gene manipulation in mice. ..