Sgk2

Summary

Gene Symbol: Sgk2
Description: SGK2, serine/threonine kinase 2
Alias: serine/threonine-protein kinase Sgk2, serum/glucocorticoid regulated kinase 2
Species: rat
Products:     Sgk2

Top Publications

  1. Gamper N, Fillon S, Feng Y, Friedrich B, Lang P, Henke G, et al. K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK. Pflugers Arch. 2002;445:60-6 pubmed
    ..Subsequently, the two homologous kinases SGK2 and SGK3 have been cloned, being products of distinct genes, which are differentially expressed and share 80% ..
  2. Won M, Park K, Byun H, Kim Y, Choi B, Hong J, et al. Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration. J Hepatol. 2009;51:67-76 pubmed publisher
    ..SGK1 expression during liver regeneration is a part of a signaling pathway that is necessary for enhancing ERK signaling activation through modulating the MEK/ERK complex formation. ..
  3. Pao A, Bhargava A, Di Sole F, Quigley R, Shao X, Wang J, et al. Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney. Am J Physiol Renal Physiol. 2010;299:F1496-506 pubmed publisher
    Serum and glucocorticoid-regulated kinase 2 (sgk2) is 80% identical to the kinase domain of sgk1, an important mediator of mineralocorticoid-regulated sodium (Na(+)) transport in the distal nephron of the kidney...