Gene Symbol: Rxylt1
Description: ribitol xylosyltransferase 1
Alias: Tmem5, transmembrane protein 5
Species: rat
Products:     Rxylt1

Top Publications

  1. Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, et al. The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. elife. 2014;3: pubmed publisher
    ..Here we show that FKRP, FKTN, TMEM5 and B4GAT1 (formerly known as B3GNT1) localize to the Golgi and contribute to the O-mannosyl post-phosphorylation ..
  2. Praissman J, Willer T, Sheikh M, Toi A, Chitayat D, Lin Y, et al. The functional O-mannose glycan on ?-dystroglycan contains a phospho-ribitol primed for matriglycan addition. elife. 2016;5: pubmed publisher
    ..b>TMEM5 is a UDP-xylosyl transferase that elaborates the structure...
  3. Manya H, Yamaguchi Y, Kanagawa M, Kobayashi K, Tajiri M, Akasaka Manya K, et al. The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol ?1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan. J Biol Chem. 2016;291:24618-24627 pubmed
    ..However, the linkage of the first Xyl residue to ribitol 5-phosphate (Rbo5P) is not clear. TMEM5 is a gene product responsible for ?-dystroglycanopathy and was reported as a potential enzyme involved in this ..

Scientific Experts