Gene Symbol: Ruvbl2
Description: RuvB-like AAA ATPase 2
Alias: ruvB-like 2, RuvB-like protein 2
Species: rat
Products:     Ruvbl2

Top Publications

  1. Ikura T, Ogryzko V, Grigoriev M, Groisman R, Wang J, Horikoshi M, et al. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell. 2000;102:463-73 pubmed
    ..These results indicate that the histone acetylase TIP60-containing complex plays a role in DNA repair and apoptosis. ..
  2. Salzer U, Kubicek M, Prohaska R. Isolation, molecular characterization, and tissue-specific expression of ECP-51 and ECP-54 (TIP49), two homologous, interacting erythroid cytosolic proteins. Biochim Biophys Acta. 1999;1446:365-70 pubmed
    ..The interaction of ECP-51 and ECP-54 with the stomatin peptide and the localization to the nucleus and cytoplasm suggest an additional function for these proteins as chaperone components. ..
  3. Petukhov M, Dagkessamanskaja A, Bommer M, Barrett T, Tsaneva I, Yakimov A, et al. Large-scale conformational flexibility determines the properties of AAA+ TIP49 ATPases. Structure. 2012;20:1321-31 pubmed publisher
    ..This might be similar to the effects of conformations adopted by TIP49 heterohexamers. ..
  4. Dalvai M, Fleury L, Bellucci L, Kocanova S, Bystricky K. TIP48/Reptin and H2A.Z requirement for initiating chromatin remodeling in estrogen-activated transcription. PLoS Genet. 2013;9:e1003387 pubmed publisher
    ..Dynamic release of gene loops could be a rapid means to remodel chromatin and to stimulate transcription in response to hormones. ..
  5. Obri A, Ouararhni K, Papin C, Diebold M, Padmanabhan K, Marek M, et al. ANP32E is a histone chaperone that removes H2A.Z from chromatin. Nature. 2014;505:648-53 pubmed publisher
    ..Z at specific chromatin control regions, in particular at enhancers and insulators. ..
  6. Mir R, Bele A, Mirza S, Srivastava S, Olou A, Ammons S, et al. A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression. Mol Cell Biol. 2015;36:886-99 pubmed publisher
    ..These studies demonstrate that interaction of ECD with RUVBL1, and its CK2-mediated phosphorylation, independent of its interaction with PIH1D1, are important for its cell cycle regulatory function. ..
  7. Wu S, Shi Y, Mulligan P, Gay F, Landry J, Liu H, et al. A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol. 2007;14:1165-72 pubmed
    ..Collectively, these observations reveal a link between YY1 and INO80 and roles for both in HRR, providing new insight into mechanisms that control the cellular response to genotoxic stress. ..
  8. Castorena C, MacKrell J, Bogan J, Kanzaki M, Cartee G. Clustering of GLUT4, TUG, and RUVBL2 protein levels correlate with myosin heavy chain isoform pattern in skeletal muscles, but AS160 and TBC1D1 levels do not. J Appl Physiol (1985). 2011;111:1106-17 pubmed publisher
    ..member 1 (TBC1D1), Tethering protein containing an UBX-domain for GLUT4 (TUG), and RuvB-like protein two (RUVBL2)] in 12 skeletal muscles or muscle regions from Wistar rats [adductor longus, extensor digitorum longus, ..