Gene Symbol: Rtn1
Description: reticulon 1
Alias: Nsp, reticulon-1, S-rex, neuroendocrine-specific protein
Baka I, Ninkina N, Pinon L, Adu J, Davies A, Georgiev G, et al
. Intracellular compartmentalization of two differentially spliced s-rex/NSP mRNAs in neurons. Mol Cell Neurosci. 1996;7:289-303 pubmed
..cerebral cortex neurons, we have isolated rat s-rex mRNAs that are analogues of the human neuroendocrine-specific NSP gene transcripts...
Hens J, Nuydens R, Geerts H, Senden N, Van de Ven W, Roebroek A, et al
. Neuronal differentiation is accompanied by NSP-C expression. Cell Tissue Res. 1998;292:229-37 pubmed
Neuroendocrine-specific protein (NSP) reticulons are expressed in neural and neuroendocrine tissues and cell cultures derived therefrom, while most other cell types lack NSP-reticulons...
Kaya L, Meissner B, Riedl M, Muik M, Schwarzer C, Ferraguti F, et al
. Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons. Biochim Biophys Acta. 2013;1833:1421-33 pubmed publisher
..In a functional assay, RTN1A significantly reduced RyR2-mediated Ca(2+) oscillations. Thus, RTN1A and RyR2 might act as functional partners in the regulation of cytosolic Ca(2+) dynamics the in neurons. ..
Ninkina N, Baka I, Buchman V. Rat and chicken s-rex/NSP mRNA: nucleotide sequence of main transcripts and expression of splice variants in rat tissues. Gene. 1997;184:205-10 pubmed
Two main transcripts of the s-rex/NSP gene are generated by different promoter usage and differential splicing in neuronal and endocrine tissues of higher vertebrates, suggesting that the encoded proteins function in neuroendocrine ..
Hirata T, Nomura T, Takagi Y, Sato Y, Tomioka N, Fujisawa H, et al
. Mosaic development of the olfactory cortex with Pax6-dependent and -independent components. Brain Res Dev Brain Res. 2002;136:17-26 pubmed
..development of the olfactory cortex, using the newly developed monoclonal antibody (mAb) 9-4c, which recognizes reticulon 1-A and -B...
Yang J, Zoeller R. Differential display identifies neuroendocrine-specific protein-A (NSP-A) and interferon-inducible protein 10 (IP-10) as ethanol-responsive genes in the fetal rat brain. Brain Res Dev Brain Res. 2002;138:117-33 pubmed
..Among them was Neuroendocrine-Specific Protein-A (NSP-A), which is known to be affected by thyroid hormone in the cortex at this developmental time...
Haas A, Yoshimura S, Stephens D, Preisinger C, Fuchs E, Barr F. Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. J Cell Sci. 2007;120:2997-3010 pubmed
Herlan L, Schulz A, Schulte L, Schulz H, HÃ¼bner N, Kreutz R. Novel candidate genes for impaired nephron development in a rat model with inherited nephron deficit and albuminuria. Clin Exp Pharmacol Physiol. 2015;42:1051-8 pubmed publisher
..Seven genes including Abcg5, Ab1-233, Efcab11, Fntb, Gpx2, Lrrn3, and Rtn1 were assigned on RNO6 and their differential expression was confirmed...