Gene Symbol: Romo1
Description: reactive oxygen species modulator 1
Alias: reactive oxygen species modulator 1
Na A, Chung Y, Lee S, Park S, Lee M, Yoo Y. A critical role for Romo1-derived ROS in cell proliferation. Biochem Biophys Res Commun. 2008;369:672-8 pubmed publisher
..We recently identified a novel protein, ROS modulator 1 (Romo1), and reported that increased expression of Romo1-triggered ROS production in the mitochondria...
Chung Y, Lee S, Kim H, Park S, Kim J, Chung J, et al
. Replicative senescence induced by Romo1-derived reactive oxygen species. J Biol Chem. 2008;283:33763-71 pubmed publisher
..Here we showed that the enforced expression of the ROS modulator 1 (Romo1) triggered premature senescence by ROS production, and this also contributed toward induction of DNA damage...
Schulz C, Schendzielorz A, Rehling P. Unlocking the presequence import pathway. Trends Cell Biol. 2015;25:265-75 pubmed publisher
..Here, we review recent advances in understanding of the mechanisms underlying protein transport along the presequence pathway. ..
Chung Y, Kim J, Yoo Y. A novel protein, Romo1, induces ROS production in the mitochondria. Biochem Biophys Res Commun. 2006;347:649-55 pubmed
..This study identified a novel protein, reactive oxygen species modulator 1 (Romo1), which is localized in the mitochondria...
Wenz L, OpaliÅ„ski Å, Wiedemann N, Becker T. Cooperation of protein machineries in mitochondrial protein sorting. Biochim Biophys Acta. 2015;1853:1119-29 pubmed publisher
..Therefore, we propose that the protein transport systems are part of a complicated protein network for mitochondrial biogenesis. ..
Liu D, Liu Y, Xia Z, Dong H, Yi Z. Reactive oxygen species modulator 1 regulates oxidative stress and induces renal and pulmonary fibrosis in a unilateral ureteral obstruction rat model and in HK?2 cells. Mol Med Rep. 2017;16:4855-4862 pubmed publisher
..Subsequently, high expression of reactive oxygen species (ROS) modulator 1 (ROMO1) and ROS was measured in blood serum...
Sha J, Zhao G, Chen X, Guan W, He Y, Wang Z. Antibacterial potential of hGlyrichin encoded by a human gene. J Pept Sci. 2012;18:97-104 pubmed publisher
..e., the absence of hetero-immunological rejection and hemolytic side effects and the unambiguous efficacy of killing pathogenic MDR bacteria, we propose hGlyrichin as a potential human antibacterial polypeptide. ..