Gene Symbol: Reep2
Description: receptor accessory protein 2
Alias: receptor expression-enhancing protein 2
Species: rat
Products:     Reep2

Top Publications

  1. Ilegems E, Iwatsuki K, Kokrashvili Z, Benard O, Ninomiya Y, Margolskee R. REEP2 enhances sweet receptor function by recruitment to lipid rafts. J Neurosci. 2010;30:13774-83 pubmed publisher
    ..We determined that REEP2 is an integral membrane protein expressed in taste cells, physically associates with both subunits of the type 1 ..
  2. Björk S, Hurt C, Ho V, Angelotti T. REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacity. PLoS ONE. 2013;8:e76366 pubmed publisher
    ..By utilizing several REEP family members (REEP1, REEP2, and REEP6) and model GPCRs (?2A and ?2C adrenergic receptors), we examined REEP regulation of GPCR plasma ..
  3. Esteves T, Durr A, Mundwiller E, Loureiro J, Boutry M, Gonzalez M, et al. Loss of association of REEP2 with membranes leads to hereditary spastic paraplegia. Am J Hum Genet. 2014;94:268-77 pubmed publisher
    ..With a combination of whole-genome mapping and exome sequencing, we identified three mutations in REEP2 in two families with HSP: a missense variant (c.107T>A [p...