Rbm5

Summary

Gene Symbol: Rbm5
Description: RNA binding motif protein 5
Alias: RNA-binding protein 5
Species: rat
Products:     Rbm5

Top Publications

  1. Kotlajich M, Hertel K. Death by splicing: tumor suppressor RBM5 freezes splice-site pairing. Mol Cell. 2008;32:162-4 pubmed publisher
    In a recent issue of Molecular Cell, Bonnal et al. (2008) demonstrate that the tumor suppressor gene RBM5 regulates alternative splicing of Fas pre-mRNA by interfering with splice-site pairing.
  2. Fushimi K, Ray P, Kar A, Wang L, Sutherland L, Wu J. Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5. Proc Natl Acad Sci U S A. 2008;105:15708-13 pubmed publisher
    ..Using a yeast RNA-protein interaction assay, we identified RBM5 (also known as LUCA-15) as a protein that binds to casp-2 pre-mRNA...
  3. Loiselle J, Sutherland L. Differential downregulation of Rbm5 and Rbm10 during skeletal and cardiac differentiation. In Vitro Cell Dev Biol Anim. 2014;50:331-9 pubmed publisher
    b>RBM5 and RBM10 play an important role in transformed cells. This role includes influencing the alternative splicing and/or expression of factors involved in apoptosis and cell cycle arrest...
  4. Zhang J, Cui Z, Feng G, Bao G, Xu G, Sun Y, et al. RBM5 and p53 expression after rat spinal cord injury: implications for neuronal apoptosis. Int J Biochem Cell Biol. 2015;60:43-52 pubmed publisher
    b>RBM5 (RNA-binding motif protein 5), a nuclear RNA binding protein, is known to trigger apoptosis and induce cell cycle arrest by regulating the activity of the tumor suppressor protein p53...