Rassf2

Summary

Gene Symbol: Rassf2
Description: Ras association domain family member 2
Alias: ras association domain-containing protein 2, Ras association (RalGDS/AF-6) domain family 2, Ras association (RalGDS/AF-6) domain family member 2
Species: rat
Products:     Rassf2

Top Publications

  1. Cooper W, Hesson L, Matallanas D, Dallol A, von Kriegsheim A, Ward R, et al. RASSF2 associates with and stabilizes the proapoptotic kinase MST2. Oncogene. 2009;28:2988-98 pubmed publisher
    b>RASSF2 is a tumour suppressor that in common with the rest of the RASSF family contains Ras association and SARAH domains...
  2. Song H, Oh S, Oh H, Lim D. Role of the tumor suppressor RASSF2 in regulation of MST1 kinase activity. Biochem Biophys Res Commun. 2010;391:969-73 pubmed publisher
    The tumor suppressor, RASSF2 (Ras association domain family 2), is frequently downregulated in a number of cancers...
  3. Song H, Kim H, Lee K, Lee D, Kim T, Song J, et al. Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice. EMBO J. 2012;31:1147-59 pubmed publisher
    b>RASSF2 belongs to the Ras-association domain family (RASSF) of proteins, which may be involved in the Hippo signalling pathway. However, the role of RASSF2 in vivo is unknown...