Gene Symbol: Pomgnt2
Description: protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
Alias: Ago61, Gtdc2, RGD1304827, protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, glycosyltransferase, glycosyltransferase-like domain containing 2, glycosyltransferase-like domain-containing protein 2
Species: rat
Products:     Pomgnt2

Top Publications

  1. Yoshida Moriguchi T, Willer T, Anderson M, Venzke D, Whyte T, Muntoni F, et al. SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science. 2013;341:896-9 pubmed publisher
    ..However, the enzymes that produce this structure have not been fully elucidated. We found that glycosyltransferase-like domain-containing 2 (GTDC2) is a protein O-linked mannose ? 1,4-N-acetylglucosaminyltransferase whose ..
  2. Yagi H, Nakagawa N, Saito T, Kiyonari H, Abe T, Toda T, et al. AGO61-dependent GlcNAc modification primes the formation of functional glycans on ?-dystroglycan. Sci Rep. 2013;3:3288 pubmed publisher
    ..A product of a recently identified causative gene for dystroglycanopathy, AGO61, acted in vitro as a protein O-mannose ?-1, 4-N-acetylglucosaminyltransferase, although it was not functionally ..
  3. Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S. Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015;5:11163 pubmed publisher
    ..Using the Pomgnt2-knockout (KO) mouse as a dystroglycanopathy model, we show that breaches of the pial basement membrane appeared ..