Gene Symbol: Phlda1
Description: pleckstrin homology-like domain, family A, member 1
Alias: Tdag, pleckstrin homology-like domain family A member 1, PQ-rich protein, PQR protein, T-cell death associated, proline- and glutamine-rich protein
Species: rat
Products:     Phlda1

Top Publications

  1. Gomes I, Xiong W, Miki T, Rosner M. A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. J Neurochem. 1999;73:612-22 pubmed
    ..The 44-kDa PQR protein, rich in PQ, PH, and QQ repeats, is homologous to a murine protein (TDAG51) required for Fas-mediated apoptosis ..
  2. Park C, Kandala G, Lee S, Choi Y. A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death. Immunity. 1996;4:583-91 pubmed
    ..Thus, TDAG51 plays an essential role in induction of apoptosis by coupling TCR stimulation to Fas expression. ..
  3. Liu F, Xu Z, Qian X, Qiu W, Huang H. Expression of Hsf1, Hsf2, and Phlda1 in cells undergoing cryptorchid-induced apoptosis in rat testes. Mol Reprod Dev. 2011;78:283-91 pubmed publisher
    ..rat testis by using DNA flow cytometry and by determining protein and mRNA expression of Hsf1, Hsf2, and Phlda1. The hypo-haploid cell fraction is significantly decreased as early as 3 days after surgical induction of ..